Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318375
Species: Mus musculus
RGD Object: Gene
Symbol: Sirt1
Name: sirtuin 1
Acc ID: CHEBI:7726
Term: octreotide
Definition: A homodetic cyclic peptide that has formula C49H66N10O10S2.
Chemical ID: MESH:D015282
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sirt1multiple interactionsEXP 6480464CTDOctreotide inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in decreased expression of SIRT1 mRNA]; SIRT1 promotes the reaction [SNHG12 mRNA promotes the reaction [Octreotide inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in decreased expression of MAP1LC3B protein]]]; SIRT1 promotes the reaction [SNHG12 mRNA results in increased susceptibility to Octreotide]; SNHG12 mRNA promotes the reaction [Octreotide inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in decreased expression of SIRT1 mRNA]]PMID:35307376
Go Back to source page   Continue to Ontology report