GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sfn | decreases methylation | ISO | Sfn (Rattus norvegicus) | 6480464 | CTD | Decitabine results in decreased methylation of SFN promoter | PMID:15979784 | Sfn | increases expression | ISO | Sfn (Rattus norvegicus) | 6480464 | CTD | Decitabine results in increased expression of SFN mRNA | PMID:15979784 | Sfn | increases expression | ISO | SFN (Homo sapiens) | 6480464 | CTD | Decitabine results in increased expression of SFN protein | PMID:22534328 PMID:25189999 | Sfn | multiple interactions | ISO | SFN (Homo sapiens) | 6480464 | CTD | [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with Decitabine] results in increased expression of SFN mRNA | PMID:22534328 | |
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