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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1312161
Species: Homo sapiens
RGD Object: Gene
Symbol: KDELR2
Name: KDEL endoplasmic reticulum protein retention receptor 2
Acc ID: CHEBI:81584
Term: 2,2',4,4'-Tetrabromodiphenyl ether
Definition: An organobromine compound that has formula C12H6Br4O.
Chemical ID: MESH:C511295
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KDELR2increases expressionEXP 6480464CTD2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of KDELR2 mRNAPMID:19095052
KDELR2affects expressionISOKdelr2 (Mus musculus)6480464CTD2,2',4,4'-tetrabromodiphenyl ether affects the expression of KDELR2 mRNAPMID:30294300
KDELR2multiple interactionsISOKdelr2 (Mus musculus)6480464CTD[Flame Retardants results in increased abundance of 2,2',4,4'-tetrabromodiphenyl ether] which results in decreased expression of KDELR2 mRNAPMID:38995820
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