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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311707
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bub1
Name: BUB1 mitotic checkpoint serine/threonine kinase
Acc ID: CHEBI:53076
Term: 4-(ethoxymethylene)-2-phenyloxazol-5-one
Definition: A 1,3-oxazole compound having a phenyl substituent at the 2-position, an ethoxymethylene group at the 4-position, and an oxo group at the 5-position. It is a chemical allergen used for immunological experiments, particularly for experiments on delayed type hypersensitivity.
Chemical ID: MESH:D010081
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bub1decreases expressionISOBUB1 (Homo sapiens)6480464CTDOxazolone results in decreased expression of BUB1 mRNAPMID:17374397
Bub1increases expressionISOBub1 (Mus musculus)6480464CTDOxazolone results in increased expression of BUB1 mRNAPMID:21404309
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