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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311469
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Clk1
Name: CDC-like kinase 1
Acc ID: CHEBI:79369
Term: elesclomol
Definition: A carbohydrazide obtained by formal condensation of the carboxy groups of malonic acid with the hydrino groups of two molar equivalents of N-methylbenzenecarbothiohydrazide
Chemical ID: MESH:C512195
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Clk1increases expressionISOCLK1 (Homo sapiens)6480464CTDelesclomol results in increased expression of CLK1 mRNAPMID:18723479
Clk1multiple interactionsISOCLK1 (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [elesclomol results in increased expression of CLK1 mRNA]PMID:18723479
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