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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311347
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pipox
Name: pipecolic acid and sarcosine oxidase
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pipoxdecreases expressionISOPIPOX (Homo sapiens)6480464CTDPhenobarbital results in decreased expression of PIPOX proteinPMID:35881160
Pipoxdecreases expressionISOPipox (Mus musculus)6480464CTDPhenobarbital results in decreased expression of PIPOX mRNA; Phenobarbital results in decreased expression of PIPOX proteinPMID:19482888 PMID:35881160
Pipoxmultiple interactionsISOPipox (Mus musculus)6480464CTDNR1I3 protein affects the reaction [Phenobarbital results in decreased expression of PIPOX mRNA]PMID:19482888
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