Pipox (pipecolic acid oxidase) - Rat Genome Database
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Gene: Pipox (pipecolic acid oxidase) Mus musculus
Analyze
Symbol: Pipox
Name: pipecolic acid oxidase
RGD ID: 1322756
MGI Page MGI
Description: Is expressed in alimentary system; liver; nervous system; and urinary system. Orthologous to human PIPOX (pipecolic acid and sarcosine oxidase); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; glutaric aciduria type I pathway; hyperlysinemia pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: L-pipecolate oxidase; L-pipecolic acid oxidase; LPIPOX; peroxisomal sarcosine oxidase; Pso
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391177,771,440 - 77,784,698 (-)NCBIGRCm39mm39
GRCm39 Ensembl1177,771,441 - 77,784,922 (-)Ensembl
GRCm381177,880,614 - 77,893,872 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1177,880,615 - 77,894,096 (-)EnsemblGRCm38mm10GRCm38
MGSCv371177,694,117 - 77,707,374 (-)NCBIGRCm37mm9NCBIm37
MGSCv361177,696,810 - 77,709,979 (-)NCBImm8
Celera1185,380,241 - 85,393,553 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
peroxisome  (IBA,IDA,ISO)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:9441754   PMID:10349636   PMID:10642506   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12904583   PMID:14561759   PMID:14610273   PMID:14681479   PMID:15489334   PMID:16141072  
PMID:16141073   PMID:17967808   PMID:18287559   PMID:18799693   PMID:21267068   PMID:21386911   PMID:21677750   PMID:21873635   PMID:27626380  


Genomics

Comparative Map Data
Pipox
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391177,771,440 - 77,784,698 (-)NCBIGRCm39mm39
GRCm39 Ensembl1177,771,441 - 77,784,922 (-)Ensembl
GRCm381177,880,614 - 77,893,872 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1177,880,615 - 77,894,096 (-)EnsemblGRCm38mm10GRCm38
MGSCv371177,694,117 - 77,707,374 (-)NCBIGRCm37mm9NCBIm37
MGSCv361177,696,810 - 77,709,979 (-)NCBImm8
Celera1185,380,241 - 85,393,553 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.74NCBI
PIPOX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1728,950,513 - 29,057,216 (+)EnsemblGRCh38hg38GRCh38
GRCh381729,043,141 - 29,057,227 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371727,370,159 - 27,384,234 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361724,394,044 - 24,408,362 (+)NCBINCBI36hg18NCBI36
Build 341724,394,043 - 24,408,362NCBI
Celera1724,229,276 - 24,243,594 (+)NCBI
Cytogenetic Map17q11.2NCBI
HuRef1723,578,154 - 23,592,473 (+)NCBIHuRef
CHM1_11727,432,423 - 27,446,741 (+)NCBICHM1_1
Pipox
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21062,769,874 - 62,783,484 (-)NCBI
Rnor_6.0 Ensembl1064,952,119 - 64,964,862 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01064,951,986 - 64,964,865 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01066,660,848 - 66,673,727 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41063,920,814 - 63,933,307 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11063,934,437 - 63,946,930 (-)NCBI
Celera1061,749,538 - 61,762,034 (-)NCBICelera
Cytogenetic Map10q25NCBI
Pipox
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554814,128,509 - 4,143,334 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554814,128,503 - 4,225,027 (-)NCBIChiLan1.0ChiLan1.0
PIPOX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11728,225,831 - 28,240,210 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1728,225,831 - 28,240,210 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01727,717,083 - 27,820,776 (-)NCBIMhudiblu_PPA_v0panPan3
PIPOX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl943,200,371 - 43,212,288 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1943,200,343 - 43,212,288 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Pipox
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365385,218,097 - 5,252,579 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC110255229
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1245,257,188 - 45,322,767 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11245,256,806 - 45,270,755 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PIPOX
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11622,805,369 - 22,820,015 (+)NCBI
ChlSab1.1 Ensembl1622,805,740 - 22,820,537 (+)Ensembl
Pipox
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247861,594,988 - 1,615,210 (+)NCBI

Position Markers
Pipox  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B5UniSTS
cM Map1144.83UniSTS
D11Bhm41  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381177,893,316 - 77,893,482UniSTSGRCm38
MGSCv371177,706,818 - 77,706,984UniSTSGRCm37
Celera1185,392,997 - 85,393,163UniSTS
Cytogenetic Map11B5UniSTS
cM Map1144.78UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170800372104800540Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177546357111546496Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116179599488808902Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116342858181939647Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170800372104800540Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117768304799486994Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170800372104800540Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172128823106128908Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170800372104800540Mouse
4141365Ltxs3_mlethal factor toxin susceptibility 3 (mouse)Not determined117768304780855532Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117231897084840636Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172835299106835463Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116718736579923086Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172927789106927907Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172927789106927907Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116342858194173092Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177546357111546496Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168300000102000000Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
12903994Opfaq3_mopen field activity QTL 3 (mouse)117384671582178599Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177880152111880273Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177172953111173092Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:473
Count of miRNA genes:267
Interacting mature miRNAs:306
Transcripts:ENSMUST00000017597, ENSMUST00000151383, ENSMUST00000155401
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000017597   ⟹   ENSMUSP00000017597
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1177,880,615 - 77,894,096 (-)Ensembl
RefSeq Acc Id: ENSMUST00000151383
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1177,881,060 - 77,882,686 (-)Ensembl
RefSeq Acc Id: ENSMUST00000155401
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1177,882,619 - 77,884,544 (-)Ensembl
RefSeq Acc Id: NM_008952   ⟹   NP_032978
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391177,771,441 - 77,784,698 (-)NCBI
GRCm381177,880,615 - 77,893,872 (-)NCBI
MGSCv371177,694,117 - 77,707,374 (-)RGD
Celera1185,380,241 - 85,393,553 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011248807   ⟹   XP_011247109
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391177,771,440 - 77,784,654 (-)NCBI
GRCm381177,880,614 - 77,893,828 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032978   ⟸   NM_008952
- UniProtKB: Q9D826 (UniProtKB/Swiss-Prot),   Q3UEJ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247109   ⟸   XM_011248807
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000017597   ⟸   ENSMUST00000017597
Protein Domains
DAO

Promoters
RGD ID:6821558
Promoter ID:MM_KWN:8641
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver,   Spleen
Transcripts:OTTMUST00000000216
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361177,695,781 - 77,696,502 (-)MPROMDB
RGD ID:6821559
Promoter ID:MM_KWN:8642
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver
Transcripts:OTTMUST00000000215
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361177,697,551 - 77,698,402 (-)MPROMDB
RGD ID:6821556
Promoter ID:MM_KWN:8643
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   ES_Cell,   Kidney,   Liver,   Lung
Transcripts:OTTMUST00000000214
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361177,707,281 - 77,707,982 (-)MPROMDB
RGD ID:8675662
Promoter ID:EPDNEW_M15859
Type:initiation region
Name:Pipox_1
Description:Mus musculus pipecolic acid oxidase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381177,893,798 - 77,893,858EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1197006 AgrOrtholog
Ensembl Genes ENSMUSG00000017453 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000017597 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000017597 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.50.50.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FAD-dep_OxRdtase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAD/NAD-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SoxA_mon UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19193 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1197006 ENTREZGENE
NCBI Gene 19193 ENTREZGENE
Pfam DAO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pipox PhenoGen
Superfamily-SCOP SSF51905 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs soxA_mon UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Q3UEJ8 ENTREZGENE, UniProtKB/TrEMBL
  Q9D826 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary O55223 UniProtKB/Swiss-Prot