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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310990
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pik3cd
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pik3cdaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of PIK3CD mRNAPMID:34747641
Pik3cddecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of PIK3CD mRNAPMID:33387578
Pik3cdincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of PIK3CD mRNAPMID:32109520
Pik3cddecreases expressionISOPik3cd (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PIK3CD mRNAPMID:19465110
Pik3cdincreases expressionISOPik3cd (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of PIK3CD mRNAPMID:20819909
Pik3cdmultiple interactionsISOPik3cd (Mus musculus)6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PIK3CD gene]PMID:20819909
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