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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310844
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dusp10
Name: dual specificity phosphatase 10
Acc ID: CHEBI:91215
Term: 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one
Definition: A member of the class of oxadiazoloquinoxalines that is 1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline substituted at position 1 by an oxo group.
Chemical ID: MESH:C095284
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dusp10multiple interactionsISODUSP10 (Homo sapiens)6480464CTD1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [andrographolide results in increased expression of DUSP10 mRNA]; 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [andrographolide results in increased expression of DUSP10 protein]PMID:29165873
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