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GENE - TERM ANNOTATION REPORT

RGD ID: 1310510
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cfhr1
Name: complement factor H-related 1
Acc ID: GO:0006956
Term: complement activation
Definition: Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
Definition Source(s): GO_REF:0000022, GOC:add, ISBN:0781735149
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cfhr1involved_inIBAMGI:88385 or PANTHER:PTN000449073 or Cfh (Rattus norvegicus) or UniProtKB:P086031600115GO_CentralGO_REF:0000033

GO_REF:0000033
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