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GENE - TERM ANNOTATION REPORT

RGD ID: 1310301
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cops5
Name: COP9 signalosome subunit 5
Acc ID: GO:0008180
Term: COP9 signalosome
Definition: A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome.
Definition Source(s): PMID:11019806, PMID:12186635, PMID:14570571
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cops5part_ofISOCOPS5 (Homo sapiens)1624291RGD PMID:18850735 PMID:19214193 PMID:25043011

PMID:18850735 PMID:19214193 PMID:25043011
Cops5part_ofISOCops5 (Mus musculus)1624291RGD PMID:9707402

PMID:9707402
Cops5part_ofIEAUniProtKB:O35864 or ensembl:ENSMUSP000000270501600115EnsemblGO_REF:0000107

GO_REF:0000107
Cops5part_ofIEAUniProtKB:Q92905 or ensembl:ENSP000003505121600115EnsemblGO_REF:0000107

GO_REF:0000107
Cops5part_ofIBAFB:FBgn0027053 or MGI:1349415 or PANTHER:PTN000045369 or PomBase:SPAC1687.13c or SGD:S000002375 or UniProtKB:Q5BBF1 or UniProtKB:Q92905 or dictyBase:DDB_G02845971600115GO_CentralGO_REF:0000033

GO_REF:0000033
Cops5part_ofIEAUniProtKB-KW:KW-07361600115UniProtGO_REF:0000043

GO_REF:0000043
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