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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309060
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Irx1
Name: iroquois homeobox 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Irx1increases expressionEXP 6480464CTDbisphenol A results in increased expression of IRX1 mRNAPMID:25181051
Irx1decreases expressionISOIrx1 (Mus musculus)6480464CTDbisphenol A results in decreased expression of IRX1 mRNAPMID:30951980
Irx1decreases expressionISOIRX1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of IRX1 mRNAPMID:33476716
Irx1increases expressionISOIrx1 (Mus musculus)6480464CTDbisphenol A results in increased expression of IRX1 mRNAPMID:37105096
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