GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sirt1 | multiple interactions | EXP | | 6480464 | CTD | puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of SIRT1 protein] | PMID:33404196 | Sirt1 | multiple interactions | ISO | SIRT1 (Homo sapiens) | 6480464 | CTD | puerarin inhibits the reaction [Lipopolysaccharides results in decreased expression of SIRT1 protein]; puerarin inhibits the reaction [Sodium Chloride results in decreased expression of SIRT1 protein]; SIRT1 protein promotes the reaction [puerarin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL18 protein]]; SIRT1 protein promotes the reaction [puerarin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; SIRT1 protein promotes the reaction [puerarin inhibits the reaction [Sodium Chloride results in decreased activity of CAT protein]]; SIRT1 protein promotes the reaction [puerarin inhibits the reaction [Sodium Chloride results in decreased activity of SOD1 protein]]; SIRT1 protein promotes the reaction [puerarin inhibits the reaction [Sodium Chloride results in decreased expression of BCL2 protein]]; SIRT1 protein promotes the reaction [puerarin inhibits the reaction [Sodium Chloride results in decreased expression of OCLN protein]]; SIRT1 protein promotes the reaction [puerarin inhibits the reaction [Sodium Chloride results in decreased expression of TJP1 protein]]; SIRT1 protein promotes the reaction [puerarin inhibits the reaction [Sodium Chloride results in increased cleavage of CASP3 protein]]; SIRT1 protein promotes the reaction [puerarin inhibits the reaction [Sodium Chloride results in increased expression of BAX protein]]; SIRT1 protein promotes the reaction [puerarin inhibits the reaction [Sodium Chloride results in increased expression of CASP1 protein]]; SIRT1 protein promotes the reaction [puerarin inhibits the reaction [Sodium Chloride results in increased expression of IL1B protein]]; SIRT1 protein promotes the reaction [puerarin inhibits the reaction [Sodium Chloride results in increased expression of IL6 protein]]; SIRT1 protein promotes the reaction [puerarin inhibits the reaction [Sodium Chloride results in increased expression of NLRP3 protein]]; SIRT1 protein promotes the reaction [puerarin inhibits the reaction [Sodium Chloride results in increased expression of PYCARD protein]]; SIRT1 protein promotes the reaction [puerarin inhibits the reaction [Sodium Chloride results in increased expression of TNF protein]] | PMID:35331853 PMID:37865300 | | ||||||||||||||||||||||
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