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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308542
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sirt1
Name: sirtuin 1
Acc ID: CHEBI:31856
Term: mithramycin
Definition: An aureolic acid that has formula C52H76O24.
Chemical ID: MESH:D008926
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sirt1multiple interactionsISOSIRT1 (Homo sapiens)6480464CTDPlicamycin inhibits the reaction [PPARD protein results in increased expression of SIRT1 mRNA]PMID:20160399
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