GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sirt1 | increases expression | EXP | | 6480464 | CTD | Oleic Acid results in increased expression of SIRT1 protein | PMID:24349266 | Sirt1 | multiple interactions | EXP | | 6480464 | CTD | [Ethanol co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of SIRT1 protein | PMID:26854922 | Sirt1 | decreases activity | ISO | SIRT1 (Homo sapiens) | 6480464 | CTD | Oleic Acid results in decreased activity of SIRT1 protein | PMID:25536389 | Sirt1 | multiple interactions | ISO | SIRT1 (Homo sapiens) | 6480464 | CTD | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [NAD promotes the reaction [Oleic Acid results in decreased activity of SIRT1 protein]]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased activity of SIRT1 protein]; NAD promotes the reaction [Oleic Acid results in decreased activity of SIRT1 protein] | PMID:25536389 | | ||||||||||||||||||||||
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