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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308314
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nlrp3
Name: NLR family, pyrin domain containing 3
Acc ID: CHEBI:60479
Term: lysophosphatidylcholine
Definition: An acylglycerophosphocholine resulting from partial hydrolysis of a phosphatidylcholine, which removes one of the fatty acyl groups. The structure is depicted in the image where R1 = acyl, R2 = H or where R1 = H, R2 = acyl.
Chemical ID: MESH:D008244
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nlrp3increases expressionISONLRP3 (Homo sapiens)6480464CTDLysophosphatidylcholines results in increased expression of NLRP3 proteinPMID:34293432
Nlrp3multiple interactionsISONLRP3 (Homo sapiens)6480464CTDGPR4 protein promotes the reaction [Lysophosphatidylcholines results in increased expression of NLRP3 protein]PMID:34293432
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