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GENE - TERM ANNOTATION REPORT

RGD ID: 1308288
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lcp1
Name: lymphocyte cytosolic protein 1
Acc ID: GO:0005884
Term: actin filament
Definition: A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
Definition Source(s): GOC:mah, ISBN:0198506732, PMID:10666339
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lcp1located_inISOLCP1 (Homo sapiens)1624291RGD PMID:16636079

PMID:16636079
Lcp1located_inISOLcp1 (Mus musculus)1624291RGD PMID:14756805

PMID:14756805
Lcp1is_active_inIBAMGI:104808 or PANTHER:PTN000462453 or UniProtKB:P137961600115GO_CentralGO_REF:0000033

GO_REF:0000033
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