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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308166
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2c79
Name: cytochrome P450, family 2, subfamily c, polypeptide 79
Acc ID: CHEBI:2676
Term: amoxicillin
Definition: A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-(4-hydroxyphenyl)acetamido group.
Chemical ID: MESH:D000658
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c79decreases activityISOCYP2C8 (Homo sapiens)6480464CTDAmoxicillin results in decreased activity of CYP2C8 proteinPMID:26763401
Cyp2c79multiple interactionsISOCYP2C8 (Homo sapiens)6480464CTDAmoxicillin inhibits the reaction [CYP2C8 protein results in decreased methylation of Aminopyrine]PMID:26763401
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