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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308041
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnfrsf10b
Name: TNF receptor superfamily member 10b
Acc ID: CHEBI:70133
Term: Ilimaquinone
Definition: A prenylquinone that has formula C22H30O4.
Chemical ID: MESH:C467077
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfrsf10bincreases expressionISOTNFRSF10A (Homo sapiens)6480464CTDilimaquinone results in increased expression of TNFRSF10A mRNA; ilimaquinone results in increased expression of TNFRSF10A proteinPMID:24930757
Tnfrsf10bmultiple interactionsISOTNFRSF10A (Homo sapiens)6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [ilimaquinone results in increased expression of TNFRSF10A mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [ilimaquinone results in increased expression of TNFRSF10A protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [ilimaquinone results in increased expression of TNFRSF10A mRNA]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [ilimaquinone results in increased expression of TNFRSF10A protein]; Acetylcysteine inhibits the reaction [ilimaquinone results in increased expression of TNFRSF10A mRNA]PMID:24930757
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