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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307618
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Csgalnact1
Name: chondroitin sulfate N-acetylgalactosaminyltransferase 1
Acc ID: CHEBI:68534
Term: enzalutamide
Definition: A benzamide obtained by formal condensation of the carboxy group of 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluorobenzoic acid with methylamine. Used for the treatment of of metastatic castration-resistant prostate cancer.
Chemical ID: MESH:C540278
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Csgalnact1decreases expressionISOCSGALNACT1 (Homo sapiens)6480464CTDenzalutamide results in decreased expression of CSGALNACT1 mRNAPMID:29581250
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