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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307142
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pls1
Name: plastin 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pls1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of PLS1 mRNAPMID:25181051 PMID:34947998
Pls1increases expressionEXP 6480464CTDbisphenol A results in increased expression of PLS1 mRNAPMID:32145629
Pls1multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Estradiol] results in increased expression of PLS1 mRNAPMID:26496021
Pls1decreases expressionISOPLS1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of PLS1 proteinPMID:31675489
Pls1decreases expressionISOPls1 (Mus musculus)6480464CTDbisphenol A results in decreased expression of PLS1 proteinPMID:35999755
Pls1increases expressionISOPls1 (Mus musculus)6480464CTDbisphenol A results in increased expression of PLS1 mRNAPMID:34585602
Pls1multiple interactionsISOPls1 (Mus musculus)6480464CTD[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of PLS1 proteinPMID:35999755
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