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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306919
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sumo1
Name: small ubiquitin-like modifier 1
Acc ID: CHEBI:7983
Term: pentobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Chemical ID: MESH:D010424
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sumo1increases expressionISOSumo1 (Mus musculus)6480464CTDPentobarbital results in increased expression of SUMO1 proteinPMID:14500579
Sumo1multiple interactionsISOSumo1 (Mus musculus)6480464CTDChorionic Gonadotropin inhibits the reaction [Pentobarbital results in increased expression of SUMO1 protein]; Pentobarbital inhibits the reaction [Gonadotropins results in decreased expression of SUMO1 protein]PMID:14500579
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