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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306565
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Map3k5
Name: mitogen-activated protein kinase kinase kinase 5
Acc ID: CHEBI:35559
Term: furan
Definition: A monocyclic heteroarene with a structure consisting of a 5-membered ring containing four carbons and one oxygen, with formula C4H4O. It is a toxic, flammable, low-boiling (31degreeC) colourless liquid.
Chemical ID: MESH:C039281
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Map3k5increases expressionEXP 6480464CTDfuran results in increased expression of MAP3K5 mRNAPMID:26194646
Map3k5increases phosphorylationISOMap3k5 (Mus musculus)6480464CTDfuran results in increased phosphorylation of MAP3K5 proteinPMID:34450210
Map3k5multiple interactionsISOMap3k5 (Mus musculus)6480464CTDrhodioloside inhibits the reaction [furan results in increased phosphorylation of MAP3K5 protein]PMID:34450210
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