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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306372
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Supt4h1
Name: SPT4 homolog, DSIF elongation factor subunit
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Supt4h1affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of SUPT4H1 mRNAPMID:22298810
Supt4h1decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of SUPT4H1 mRNAPMID:34747641
Supt4h1affects expressionISOSupt4a (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of SUPT4H1 mRNAPMID:21570461
Supt4h1decreases expressionISOSUPT4H1 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of SUPT4H1 mRNAPMID:11007951
Supt4h1multiple interactionsISOSUPT4H1 (Homo sapiens)6480464CTDCycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SUPT4H1 mRNA]PMID:11007951
Supt4h1multiple interactionsISOSupt4a (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the reaction [AHR protein binds to SUPT4H1 promoter]PMID:19654925
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