Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305970
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cd68
Name: Cd68 molecule
Acc ID: CHEBI:9288
Term: streptozocin
Definition: An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Chemical ID: MESH:D013311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cd68increases expressionEXP 6480464CTDStreptozocin results in increased expression of CD68 proteinPMID:29291386
Cd68multiple interactionsEXP 6480464CTD[resveratrol co-treated with Streptozocin] results in increased expression of CD68 mRNA; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of CD68 protein]PMID:25905778 PMID:29291386
Cd68increases expressionISOCd68 (Mus musculus)6480464CTDStreptozocin results in increased expression of CD68 mRNAPMID:30184259
Cd68multiple interactionsISOCd68 (Mus musculus)6480464CTDAM6545 inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]]PMID:30184259
Go Back to source page   Continue to Ontology report