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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305476
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mki67
Name: marker of proliferation Ki-67
Acc ID: CHEBI:27889
Term: lead(0)
Definition: An elemental lead that has formula Pb.
Chemical ID: MESH:D007854
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mki67multiple interactionsEXP 6480464CTD[lead acetate results in increased abundance of Lead] which results in decreased expression of MKI67 protein; Resveratrol inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of MKI67 protein]PMID:33978298
Mki67affects expressionISOMKI67 (Homo sapiens)6480464CTDLead affects the expression of MKI67 mRNAPMID:28903495
Mki67decreases expressionISOMKI67 (Homo sapiens)6480464CTDLead results in decreased expression of MKI67 proteinPMID:32004626
Mki67multiple interactionsISOMKI67 (Homo sapiens)6480464CTDLead inhibits the reaction [[Progesterone co-treated with Estrogens] results in decreased expression of MKI67 protein]PMID:32004626
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