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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305471
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atf6
Name: activating transcription factor 6
Acc ID: CHEBI:3962
Term: curcumin
Definition: A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa.
Chemical ID: MESH:D003474
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atf6increases expressionISOATF6 (Homo sapiens)6480464CTDCurcumin results in increased expression of ATF6 mRNAPMID:29723631
Atf6increases expressionISOAtf6 (Mus musculus)6480464CTDCurcumin results in increased expression of ATF6 proteinPMID:21793155
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