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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305332
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mdm2
Name: MDM2 proto-oncogene
Acc ID: CHEBI:16602
Term: trichloroethene
Definition: A member of the class of chloroethenes that is ethene substituted by chloro groups at positions 1, 1 and 2.
Chemical ID: MESH:D014241
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mdm2increases expressionEXP 6480464CTDTrichloroethylene results in increased expression of MDM2 mRNAPMID:33387578
Mdm2multiple interactionsEXP 6480464CTD[Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of MDM2 mRNAPMID:17905399
Mdm2affects expressionISOMdm2 (Mus musculus)6480464CTDTrichloroethylene affects the expression of MDM2 mRNAPMID:21135412
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