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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305299
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Arid3a
Name: AT-rich interaction domain 3A
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Arid3aaffects methylationISOARID3A (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of ARID3A intronPMID:30157460
Arid3adecreases methylationISOArid3a (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased methylation of ARID3A intronPMID:27901495
Arid3aincreases expressionISOARID3A (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of ARID3A mRNAPMID:32234424
Arid3aincreases methylationISOARID3A (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of ARID3A 3' UTR; Benzo(a)pyrene results in increased methylation of ARID3A 5' UTR; Benzo(a)pyrene results in increased methylation of ARID3A promoterPMID:27901495
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