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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305008
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Suclg2
Name: succinate-CoA ligase GDP-forming subunit beta
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Suclg2decreases expressionISOSUCLG2 (Homo sapiens)6480464CTDDoxorubicin results in decreased expression of SUCLG2 mRNAPMID:29803840
Suclg2decreases expressionISOSuclg2 (Mus musculus)6480464CTDDoxorubicin results in decreased expression of SUCLG2 mRNA; Doxorubicin results in decreased expression of SUCLG2 proteinPMID:21251210 PMID:26873546
Suclg2multiple interactionsISOSuclg2 (Mus musculus)6480464CTDsodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of SUCLG2 protein]PMID:21251210
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