GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nqo2 | affects response to substance | ISO | Nqo2 (Mus musculus) | 6480464 | CTD | NQO2 affects the susceptibility to Vitamin K 3 | PMID:12351651 | Nqo2 | decreases response to substance | ISO | Nqo2 (Mus musculus) | 6480464 | CTD | NQO2 gene mutant form results in decreased susceptibility to Vitamin K 3 | PMID:21859103 | Nqo2 | increases activity | ISO | Nqo2 (Mus musculus) | 6480464 | CTD | NQO2 protein results in increased activity of Vitamin K 3 | PMID:17762829 | Nqo2 | increases reduction | ISO | NQO2 (Homo sapiens) | 6480464 | CTD | NQO2 protein results in increased reduction of Vitamin K 3 | PMID:29281794 | Nqo2 | multiple interactions | ISO | NQO2 (Homo sapiens) | 6480464 | CTD | [NQO2 protein results in increased oxidation of 1-benzyl-1,4-dihydronicotinamide] which results in increased reduction of Vitamin K 3; [NQO2 protein results in increased oxidation of nicotinamide-beta-riboside] which results in increased reduction of Vitamin K 3; Amodiaquine inhibits the reaction [NQO2 protein results in increased reduction of Vitamin K 3]; chrysoeriol inhibits the reaction [[NQO2 protein results in increased oxidation of 1-benzyl-1,4-dihydronicotinamide] which results in increased reduction of Vitamin K 3]; chrysoeriol inhibits the reaction [[NQO2 protein results in increased oxidation of nicotinamide-beta-riboside] which results in increased reduction of Vitamin K 3]; Clozapine inhibits the reaction [NQO2 protein results in increased reduction of Vitamin K 3]; Mefenamic Acid inhibits the reaction [NQO2 protein results in increased reduction of Vitamin K 3]; Melatonin inhibits the reaction [[NQO2 protein results in increased oxidation of 1-benzyl-1,4-dihydronicotinamide] which results in increased reduction of Vitamin K 3]; Melatonin inhibits the reaction [[NQO2 protein results in increased oxidation of nicotinamide-beta-riboside] which results in increased reduction of Vitamin K 3]; N-(2-(2-methoxy-6H-dipyrido(2,3-a-3,2-e)pyrrolizin-11-yl)ethyl)-2-furamide inhibits the reaction [[NQO2 protein results in increased oxidation of 1-benzyl-1,4-dihydronicotinamide] which results in increased reduction of Vitamin K 3]; N-(2-(2-methoxy-6H-dipyrido(2,3-a-3,2-e)pyrrolizin-11-yl)ethyl)-2-furamide inhibits the reaction [[NQO2 protein results in increased oxidation of nicotinamide-beta-riboside] which results in increased reduction of Vitamin K 3]; Resveratrol inhibits the reaction [[NQO2 protein results in increased oxidation of 1-benzyl-1,4-dihydronicotinamide] which results in increased reduction of Vitamin K 3]; Resveratrol inhibits the reaction [[NQO2 protein results in increased oxidation of nicotinamide-beta-riboside] which results in increased reduction of Vitamin K 3]; Resveratrol inhibits the reaction [NQO2 protein results in increased reduction of Vitamin K 3] | PMID:20399199 PMID:29281794 | | ||||||||||||||||||||||
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