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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303178
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nanog
Name: Nanog homeobox
Acc ID: CHEBI:34785
Term: heptachlor
Definition: A cyclodiene organochlorine insecticide that is 3a,4,7,7a-tetrahydro-1H-4,7-methanoindene substituted by chlorine atoms at positions 1, 4, 5, 6, 7, 8 and 8. Formerly used to kill termites, ants and other insects in agricultural and domestic situations.
Chemical ID: MESH:D006533
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nanogmultiple interactionsISONANOG (Homo sapiens)6480464CTDHeptachlor inhibits the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in decreased expression of NANOG mRNA]PMID:32949729
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