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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303107
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vkorc1
Name: vitamin K epoxide reductase complex, subunit 1
Acc ID: CHEBI:134975
Term: fluindione
Definition: null
Chemical ID: MESH:C017673
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vkorc1decreases activityISOVKORC1 (Homo sapiens)6480464CTDfluindione results in decreased activity of VKORC1 proteinPMID:29581108
Vkorc1multiple interactionsISOVKORC1 (Homo sapiens)6480464CTDfluindione inhibits the reaction [VKORC1 protein results in increased reduction of Vitamin K 1]; fluindione inhibits the reaction [VKORC1 protein results in increased reduction of vitamin K1 oxide]PMID:29581108
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