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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303075
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsp90ab1
Name: heat shock protein 90 alpha family class B member 1
Acc ID: CHEBI:35696
Term: cobalt dichloride
Definition: A cobalt salt in which the cobalt metal is in the +2 oxidation state and the counter-anion is chloride. It is used as an indicator for water in desiccants.
Chemical ID: MESH:C018021
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsp90ab1increases expressionISOHSP90AB1 (Homo sapiens)6480464CTDcobaltous chloride results in increased expression of HSP90AB1 mRNAPMID:17553155
Hsp90ab1multiple interactionsISOHSP90AB1 (Homo sapiens)6480464CTDcobaltous chloride promotes the reaction [HIF1A protein binds to HSP90AB1 protein]PMID:29355601
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