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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303031
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Crat
Name: carnitine O-acetyltransferase
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cratincreases expressionEXP 6480464CTDperfluorooctanoic acid results in increased expression of CRAT mRNAPMID:28511854
Cratincreases expressionISOCRAT (Homo sapiens)6480464CTDperfluorooctanoic acid results in increased expression of CRAT mRNA; perfluorooctanoic acid results in increased expression of CRAT proteinPMID:23978341 PMID:25868421 PMID:26879310
Cratincreases expressionISOCrat (Mus musculus)6480464CTDperfluorooctanoic acid results in increased expression of CRAT mRNAPMID:17681415 PMID:23626681 PMID:28558994 PMID:30508572 PMID:30711707
Cratmultiple interactionsISOCrat (Mus musculus)6480464CTDDietary Fats, Unsaturated inhibits the reaction [perfluorooctanoic acid results in increased expression of CRAT mRNA]PMID:23626681
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