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GENE - TERM ANNOTATION REPORT

RGD ID: 12248301
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: ENG
Name: endoglin
Acc ID: DOID:0050855
Term: renal fibrosis
Definition: A kidney disease that is characterized by progressive detrimental connective tissue deposition of the kidney parenchyma leading to deterioration of renal function. (DO)
Definition Source(s): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776335/ "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ENG ISOEng (Rattus norvegicus)9068941RGDassociated with Ureteral Obstruction; mRNA, protein:increased expression:kidney (rat)PMID:16440600 REF_RGD_ID:7248781
ENG ISOEng (Mus musculus)9068941RGDprotein:altered expression:kidney (mouse)PMID:15033991 REF_RGD_ID:7248783
ENGtreatmentISOEng (Rattus norvegicus)9068941RGD PMID:15475654 REF_RGD_ID:7248782
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