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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 12063362
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: ABCB1
Name: ATP binding cassette subfamily B member 1
Acc ID: CHEBI:8985
Term: SDZ PSC 833
Definition: A homodetic cyclic peptide that has formula C63H111N11O12.
Chemical ID: MESH:C070272
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ABCB1multiple interactionsEXP 6480464CTDvalspodar inhibits the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]; valspodar inhibits the reaction [ABCB1 protein affects the susceptibility to Vincristine]; valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]PMID:15492788 PMID:24975508
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