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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11440
Species: Mus musculus
RGD Object: Gene
Symbol: Trp53
Name: transformation related protein 53
Acc ID: CHEBI:53001
Term: nickel sulfate
Definition: A metal sulfate having nickel(2+) as the metal ion.
Chemical ID: MESH:C029938
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trp53increases expressionISOTP53 (Homo sapiens)6480464CTDnickel sulfate results in increased expression of TP53 proteinPMID:21776270 PMID:23568779
Trp53multiple interactionsISOTP53 (Homo sapiens)6480464CTDnickel sulfate inhibits the reaction [Potassium Dichromate results in increased phosphorylation of TP53 protein]PMID:20493934
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