GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | multiple interactions | EXP | | 6480464 | CTD | geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]; manumycin inhibits the reaction [Acetaminophen results in increased expression of TNF mRNA]; manumycin inhibits the reaction [Acetaminophen results in increased expression of TNF protein] | PMID:19739265 PMID:21430599 | Tnf | decreases response to substance | ISO | TNF (Homo sapiens) | 6480464 | CTD | manumycin results in decreased susceptibility to TNF protein | PMID:21211511 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | manumycin inhibits the reaction [TNF protein results in increased expression of MMP13 mRNA]; manumycin inhibits the reaction [TNF protein results in increased expression of MMP13 protein] | PMID:21211511 | | ||||||||||||||||||||||
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