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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11379
Species: Mus musculus
RGD Object: Gene
Symbol: Tac1
Name: tachykinin 1
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tac1decreases expressionEXP 6480464CTDBenzo(a)pyrene results in decreased expression of TAC1 mRNAPMID:23735875
Tac1increases expressionEXP 6480464CTDBenzo(a)pyrene results in increased expression of TAC1 mRNAPMID:19770486 PMID:23735875
Tac1decreases expressionISOTac1 (Rattus norvegicus)6480464CTDBenzo(a)pyrene results in decreased expression of TAC1 mRNAPMID:21839799
Tac1decreases methylationISOTAC1 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of TAC1 promoterPMID:27901495
Tac1increases expressionISOTAC1 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of TAC1 mRNAPMID:20106945 PMID:32234424
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