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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11070
Species: Mus musculus
RGD Object: Gene
Symbol: Pdgfrb
Name: platelet derived growth factor receptor, beta polypeptide
Acc ID: CHEBI:28939
Term: N-acetyl-L-cysteine
Definition: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Chemical ID: MESH:D000111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdgfrbmultiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [sodium arsenite results in increased expression of PDGFRB mRNA]PMID:21134390
Pdgfrbmultiple interactionsISOPDGFRB (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of PDGFRB mRNA]; Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of PDGFRB protein]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of PDGFRB mRNA]]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of PDGFRB protein]]PMID:23392711
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