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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10997
Species: Mus musculus
RGD Object: Gene
Symbol: Nos3
Name: nitric oxide synthase 3, endothelial cell
Acc ID: CHEBI:48416
Term: olmesartan
Definition: A biphenylyltetrazole that has formula C24H26N6O3.
Chemical ID: MESH:C097933
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nos3multiple interactionsISONos3 (Rattus norvegicus)6480464CTDolmesartan promotes the reaction [NOS3 protein binds to NOS3 protein]; olmesartan results in increased activity of and results in increased phosphorylation of NOS3 protein; Pravastatin promotes the reaction [olmesartan results in increased activity of and results in increased phosphorylation of NOS3 protein]PMID:17170375
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