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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10996
Species: Mus musculus
RGD Object: Gene
Symbol: Nos2
Name: nitric oxide synthase 2, inducible
Acc ID: CHEBI:9464
Term: testosterone enanthate
Definition: An enanthate ester that has formula C26H40O3.
Chemical ID: MESH:C004648
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nos2increases expressionISONos2 (Rattus norvegicus)6480464CTDtestosterone enanthate results in increased expression of NOS2 mRNA; testosterone enanthate results in increased expression of NOS2 proteinPMID:20463352 PMID:23085480
Nos2multiple interactionsISONos2 (Rattus norvegicus)6480464CTD[pimagedine inhibits the reaction [testosterone enanthate results in increased expression of NOS2 mRNA]] which results in decreased secretion of Nitrites; [pimagedine inhibits the reaction [testosterone enanthate results in increased expression of NOS2 mRNA]] which results in increased secretion of Dihydrotestosterone; [pimagedine inhibits the reaction [testosterone enanthate results in increased expression of NOS2 mRNA]] which results in increased secretion of Testosterone; [testosterone enanthate results in increased expression of NOS2 mRNA] which results in increased abundance of Cyclic GMP; [testosterone enanthate results in increased expression of NOS2 mRNA] which results in increased abundance of Nitrites; Cyproterone Acetate inhibits the reaction [testosterone enanthate results in increased expression of NOS2 mRNA]; Cyproterone Acetate inhibits the reaction [testosterone enanthate results in increased expression of NOS2 protein]; pimagedine inhibits the reaction [testosterone enanthate results in increased expression of NOS2 mRNA]; testosterone enanthate inhibits the reaction [Triptorelin Pamoate inhibits the reaction [testosterone enanthate results in increased expression of NOS2 mRNA]]; testosterone enanthate inhibits the reaction [Triptorelin Pamoate inhibits the reaction [testosterone enanthate results in increased expression of NOS2 protein]]; Triptorelin Pamoate inhibits the reaction [testosterone enanthate results in increased expression of NOS2 mRNA]; Triptorelin Pamoate inhibits the reaction [testosterone enanthate results in increased expression of NOS2 protein]PMID:20463352 PMID:23085480
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