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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10996
Species: Mus musculus
RGD Object: Gene
Symbol: Nos2
Name: nitric oxide synthase 2, inducible
Acc ID: CHEBI:77249
Term: rosuvastatin calcium
Definition: An organic calcium salt that is the hemicalcium salt of rosuvastatin.
Chemical ID: MESH:D000068718
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nos2increases expressionISONos2 (Rattus norvegicus)6480464CTDRosuvastatin Calcium results in increased expression of NOS2 mRNAPMID:21443142
Nos2multiple interactionsISONos2 (Rattus norvegicus)6480464CTDRosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of NOS2 mRNA]PMID:32007421 PMID:35130744
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