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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10865
Species: Mus musculus
RGD Object: Gene
Symbol: Lepr
Name: leptin receptor
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Leprmultiple interactionsEXP 6480464CTDResveratrol inhibits the reaction [Dietary Fats results in increased expression of LEPR mRNA]; Resveratrol inhibits the reaction [Dietary Fats results in increased expression of LEPR protein]; Resveratrol inhibits the reaction [LEPR gene mutant form results in decreased susceptibility to Acetylcholine]; Resveratrol inhibits the reaction [LEPR gene mutant form results in increased abundance of Superoxides]PMID:19478208 PMID:31881177
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