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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10857
Species: Mus musculus
RGD Object: Gene
Symbol: Lamp2
Name: lysosomal-associated membrane protein 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lamp2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of LAMP2 mRNA; bisphenol A results in decreased expression of LAMP2 proteinPMID:33221593 PMID:34186417
Lamp2multiple interactionsEXP 6480464CTDcoenzyme Q10 inhibits the reaction [bisphenol A results in decreased expression of LAMP2 protein]PMID:34186417
Lamp2decreases expressionISOLamp2 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of LAMP2 mRNAPMID:30816183
Lamp2decreases expressionISOLAMP2 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of LAMP2 proteinPMID:34186270 PMID:37664457
Lamp2increases expressionISOLamp2 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of LAMP2 mRNAPMID:25181051 PMID:33296240
Lamp2multiple interactionsISOLAMP2 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of LAMP2 genePMID:31601247
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