Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	10812
Species:	Mus musculus
RGD Object:	Gene
Symbol:	Ins2
Name:	insulin II

Acc ID:	CHEBI:61057
Term:	tacrolimus hydrate
Definition:	A hydrate that is the monohydrate form of tacrolimus.
Chemical ID:	MESH:D016559

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Ins2	decreases expression	ISO	INS (Homo sapiens)	6480464	CTD	Tacrolimus results in decreased expression of INS protein	PMID:17391142

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.