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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10796
Species: Mus musculus
RGD Object: Gene
Symbol: Il4
Name: interleukin 4
Acc ID: CHEBI:50648
Term: 9-cis-retinoic acid
Definition: A retinoic acid in which the exocyclic double bonds have 7E,9Z,11E,13E geometry.
Chemical ID: MESH:C103303
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il4increases secretionEXP 6480464CTDAlitretinoin results in increased secretion of IL4 proteinPMID:11970994
Il4multiple interactionsEXP 6480464CTDIL4 protein promotes the reaction [Alitretinoin results in increased secretion of IL4 protein]PMID:11970994
Il4increases expressionISOIL4 (Homo sapiens)6480464CTDAlitretinoin results in increased expression of IL4 mRNA; Alitretinoin results in increased expression of IL4 proteinPMID:17118196
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