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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10796
Species: Mus musculus
RGD Object: Gene
Symbol: Il4
Name: interleukin 4
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il4decreases expressionEXP 6480464CTDpirinixic acid results in decreased expression of IL4 mRNAPMID:17888025 PMID:18249437
Il4multiple interactionsEXP 6480464CTD[Picryl Chloride co-treated with pirinixic acid] results in decreased expression of IL4 protein; PPARA protein affects the reaction [[Picryl Chloride co-treated with pirinixic acid] results in decreased expression of IL4 protein]PMID:17371993
Il4increases expressionISOIl4 (Rattus norvegicus)6480464CTDpirinixic acid results in increased expression of IL4 mRNAPMID:19782605
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