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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10790
Species: Mus musculus
RGD Object: Gene
Symbol: Il1b
Name: interleukin 1 beta
Acc ID: CHEBI:7596
Term: nitroprusside
Definition: An iron coordination entity that has formula C5FeN6O.
Chemical ID: MESH:D009599
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1bmultiple interactionsISOIL1B (Homo sapiens)6480464CTDNitroprusside inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; Nitroprusside inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 protein]; Nitroprusside inhibits the reaction [MIR135B mRNA inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased secretion of IL1B protein]]PMID:11076874 PMID:28484287
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